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The 50 Most-Frequently Cited Articles
in J Pharmacol Exp Ther as of December 1, 2008 -- updated monthly

Most-cited rankings are recalculated at the beginning of the month.
Rankings are based on citations to articles on this journal site from articles in HighWire-hosted journals.

1.  T Shimada, H Yamazaki, M Mimura, Y Inui, FP Guengerich
  Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians
  J. Pharmacol. Exp. Ther. Jul 01, 1994; 270: 414-423.
(In "ARTICLES")   [Abstract]     [PDF]
 
2.  Elisabeth Buchdunger, Catherine L. Cioffi, Norman Law, David Stover, Sayuri Ohno-Jones, Brian J. Druker, Nicholas B. Lydon
  Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  J. Pharmacol. Exp. Ther. Oct 01, 2000; 295: 139-145.
(In "CELLULAR AND MOLECULAR PHARMACOLOGY")   [Abstract]     [Full Text]     [PDF]
 
3.  LJ Ignarro, H Lippton, JC Edwards, WH Baricos, AL Hyman, PJ Kadowitz, CA Gruetter
  Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates
  J. Pharmacol. Exp. Ther. Sep 01, 1981; 218: 739-749.
(In "ARTICLES")   [PDF]
 
4.  JE Bleasdale, NR Thakur, RS Gremban, GL Bundy, FA Fitzpatrick, RJ Smith, S Bunting
  Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils
  J. Pharmacol. Exp. Ther. Nov 01, 1990; 255: 756-768.
(In "ARTICLES")   [Abstract]     [PDF]
 
5.  FRED E. D''AMOUR, DONN L. SMITH
  A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
  J. Pharmacol. Exp. Ther. May 01, 1941; 72: 74-79.
(In "ARTICLES")   [Abstract]     [PDF]
 
6.  M Alkondon, EX Albuquerque
  Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes
  J. Pharmacol. Exp. Ther. Jun 01, 1993; 265: 1455-1473.
(In "ARTICLES")   [Abstract]     [PDF]
 
7.  RJ Smith, LM Sam, JM Justen, GL Bundy, GA Bala, JE Bleasdale
  Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness
  J. Pharmacol. Exp. Ther. May 01, 1990; 253: 688-697.
(In "ARTICLES")   [Abstract]     [PDF]
 
8.  J. T. LITCHFIELD, F. WILCOXON
  A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS
  J. Pharmacol. Exp. Ther. Jun 01, 1949; 96: 99-113.
(In "ARTICLES")   [Abstract]     [PDF]
 
9.  M Clozel, V Breu, GA Gray, B Kalina, BM Loffler, K Burri, JM Cassal, G Hirth, M Muller, W Neidhart
  Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist
  J. Pharmacol. Exp. Ther. Jul 01, 1994; 270: 228-235.
(In "ARTICLES")   [Abstract]     [PDF]
 
10.  WR Martin, CG Eades, JA Thompson, RE Huppler, PE Gilbert
  The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog
  J. Pharmacol. Exp. Ther. Jun 01, 1976; 197: 517-532.
(In "ARTICLES")   [Abstract]     [PDF]
 
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Last Updated: 12/09/2008 15:08:37


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